Modified PEEK has great potential in medical implantation

Biomedical materials are a highly skilled industry with many cross disciplines and intensive common sense, including metal, polymer materials, composite materials, etc. In the meantime, medical polymer materials are the materials that have been developed early, widely used, and widely used in biomedical materials, and are also a rapidly developing category. With the development of the implant market, PEEK (polyetheretherketone), as a new type of medical implant materials, has been used in plastic surgery, cardiovascular, artificial spine and other fields.

PEEK spinal fusion device is expected to be made in China PEEK

It is reported that the incidence rate of cervical spondylosis in China's population is about 7%, and the cervical health problems of nearly 100 million people can not be ignored. China introduced artificial disc replacement in 2003, mainly using imported products. It is estimated that the demand for artificial intervertebral discs in China will be more than 30000 to 60000 sets in the next few years, with a market value of about 3.7 billion yuan!

Dr. Shang Peng of Shenzhen Advanced Skills Research Institute of Chinese Academy of Sciences shared the project of "Research on Surface Modified PEEK Artificial Intervertebral Disc and Biomechanics" at the 4th Biomedical Information Conference Forum held by MEDTEC (China International Medical Equipment Planning and Skills Exhibition) on March 15, 2016, indicating that the Institute has planned a surface bioactive A new type of artificial cervical intervertebral disc with biological fixation can be formed.

More powerful function of modified PEEK

According to Dr. Shang Peng, the adsorption and cross-linking of type I collagen can improve the surface hydrophobicity of PEEK data and the adhesion and proliferation of cells. The coupling of BMP-2 can promote the annual payment, proliferation and cell decomposition ability of cells on the surface of PEED data. Zui final experiment proved that the modified materials had better biocompatibility and bone fusion ability than the unmodified materials.

Recently, Solvay, a supplier of high functional polymer materials, announced that Zeniva Polyether Ether Ketone (PEEK), one of the four products in Solviva's implant level biological data series, had successfully passed the biocompatibility test of Tianjin Medical Device Quality Supervision and Inspection Center of China Food and Drug Administration. The institution has conducted strict tests on Zeniva PEEK's characteristics, such as sensitization, intradermal toxicity, systemic acute toxicity, subchronic toxicity, genetic toxicity and bone implant compatibility, to ensure the biological safety of the data in human body. For all implantable medical devices, the safety is di first. It can be seen that the use of modified PEEK in the field of medical implantation should not be underestimated.

PEEK Other medical occasions

PEEK has a modulus very close to that of bone itself, and has good toughness and fatigue resistance. In the use of intervertebral equipment, PEEK has more advantages than titanium, cobalt chromium alloy metal materials. It has many advantages such as biocompatibility, chemical stability and elastic modulus near bone itself. With the development of implant market, PEEK has been used in more other fields, such as plastic surgery, cardiovascular, pharmaceutical, etc.

Because PEEK has electrical insulation properties and excellent mechanical functions, the cardiovascular sector is using PEEK as an installation component and an independent implant. In the pharmaceutical field, compared with other plastics, PEEK is a material with chemical resistance of body fluids. When used for injection molding, the material is light in weight, high in component integration, and has greater freedom in planning.